Molecular features of early onset adult myelodysplastic syndrome

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منابع مشابه

Molecular features of early onset adult myelodysplastic syndrome

Myelodysplastic syndromes are typically diseases of older adults. Patients in whom the onset is early may have distinct molecular and clinical features or reflect a demographic continuum. The identification of differences between "early onset" patients and those diagnosed at a traditional age has the potential to advance understanding of the pathogenesis of myelodysplasia and may lead to format...

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Mazaheri Sh1, Fazlian MM2, Hossein Zadeh A3 1. Assistant Professor, Department of Neurology, Faculty of medicine, Hamedan University of Medical Sciences 2. General practitioner, Specialty and Subspecialty Hospital of Besat, Hamedan University of Medical Sciences 3. General practitioner, Hamedan Health Center Abstract Background: Multiple Sclerosis (MS) is one of the most common causes of chr...

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Important features of myelodysplastic syndrome.

Myelodysplastic syndromes (MDS) are characterized by peripheral cytopenias in combination with a hyperplastic bone marrow. During the last 15 years, important progress has been made in the understanding of the biology and prognosis of myelodysplastic syndromes. The classification according to the World Health Organization (WHO) includes mainly morphological criteria and is supplemented by the I...

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Molecular Profiling in Confirming the Diagnosis of Early Myelodysplastic Syndrome

Background: Diagnosis of myelodysplastic syndrome (MDS) based on bone marrow morphology can be very difficult when blasts are not increased. The demonstration of cytogenetic abnormalities in these cases can confirm the diagnosis, providing cytopenia is documented. Cytopenia is usually the major reason for initiating work-up for myelodysplasia and, in general, cases with unicytopenia are the mos...

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ژورنال

عنوان ژورنال: Haematologica

سال: 2017

ISSN: 0390-6078,1592-8721

DOI: 10.3324/haematol.2016.159772